College football odds, picks, predictions, best bets for Week 8: Proven computer model backs Clemson, Iowa – CBS Sports

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One of the marquee matchups on the Week 8 college football schedule features Dorian Thompson-Robinson and the ninth-ranked UCLA Bruins traveling to face Bo Nix and the 10th-ranked Oregon Ducks. Thompson-Robinson has thrown at least three touchdown passes in three of his last four games, helping the Bruins average 41.5 points per contest. Meanwhile, the Ducks have reeled off five consecutive wins after losing their season opener against Georgia.
The latest Week 8 college football odds from Caesars Sportsbook list the Ducks as 6-point favorites at home. Elsewhere in the Pac-12, the Stanford Cardinal are 3-point favorites against Arizona State after upsetting Notre Dame on the road last Saturday. Before locking in any Week 8 college football picks on those games or others around the nation, be sure to see the latest college football predictions from SportsLine’s advanced computer model.
The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.
Now, it has turned its attention to the latest Week 8 college football odds from Caesars and locked in picks for every FBS matchup. Head here to see every pick.
One of the college picks the model is high on in Week 8: No. 5 Clemson (-13.5) cruises to a blowout win against No. 14 Syracuse on Saturday afternoon. The Tigers are coming off an impressive 34-28 win over Florida State. The game was all but wrapped up with the Tigers leading 34-14 heading into the fourth quarter. 
Quarterback DJ Uiagalelei continued his impressive season, throwing for 203 yards, three touchdowns and zero interceptions against the Seminoles. He also recorded 14 carries for 26 yards and another score. For the season, Uiagalelei has thrown for 1,665 yards, 17 touchdowns and just two interceptions, while averaging 4.2 yards per carry. Plus, Clemson is 7-1 against the spread in its last eight games against an ACC opponent, which is one reason why the model expects the Tigers to cover the spread 60% of the time. 
Another one of the model’s top college football picks: Iowa (+29.5) keeps things close enough to cover the spread on the road when it faces No. 2 Ohio State at noon ET. The Hawkeyes feature one of the nation’s stingiest defenses. In fact, Iowa is giving up just 9.83 points per game this season, which ranks third in the country.
The Buckeyes are clearly the better team in this matchup, but covering such a large spread could be hard to accomplish against an Iowa defense that is giving up just 154 passing yards per game this season. Plus, the Hawkeyes are 3-0-1 against the spread in their last four meetings against Ohio State. SportsLine’s model expects that trend to continue on Saturday, as Iowa covers the spread almost 70% of the time. See which other teams the model likes here.
The model has also made the call on who wins and covers in every other FBS matchup in Week 8, and it says a top-20 favorite will go down hard. You can only get every pick for every game at SportsLine.
So what college football picks can you make with confidence? And which top-20 favorite goes down hard? Check out the latest college football odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned almost $3,000 in profit over the past six-plus seasons, and find out.
See full Week 8 college football picks, odds, predictions here
Thursday, Oct. 20
Virginia at Georgia Tech (-3.5, 45.5)
Troy at South Alabama (-3, 48.5)
Friday, Oct. 21
UAB at Western Kentucky (-2.5, 57.5)
Tulsa at Temple (+13, 52.5)
Saturday, Oct. 22
Iowa at Ohio State (-29.5, 49)
Syracuse at Clemson (-13.5, 51)
Indiana at Rutgers (-3, 45)
Kansas at Baylor (-8.5, 63)
 Cincinnati at SMU (+3, 63)
Duke at Miami (-8, 60.5)
West Virginia at Texas Tech (-6, 68.5)
Northwestern at Maryland (-13.5, 52.5)
Boston College at Wake Forest (-21, 61.5)
Ole Miss at LSU (PK, 64.5)
Texas at Oklahoma State
 Purdue at Wisconsin (-2, 52.5)
UCLA at Oregon (-6, 70.5)
Memphis at Tulane (-7, 56.5)
Vanderbilt at Missouri (-14, 55)
Mississippi State at Alabama (-21, 62)
Minnesota at Penn State (-4.5, 45)
Texas A&M at South Carolina (+3.5, 45)
Kansas State at TCU (-4.5, 59)
Pittsburgh at Louisville (-1, 56.5)
Washington at Cal (+7.5, 57)
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