Colts vs. Chargers odds, line, spread: Monday Night Football picks, NFL predictions, best bets by proven model – CBS Sports
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Lucas Oil Stadium is the center of the NFL world as it hosts Monday Night Football. The Indianapolis Colts welcome the Los Angeles Chargers in the finale of the Week 16 NFL schedule. The Colts are aiming to stop a four-game losing streak, and Indianapolis is 4-9-1 overall this season. The Chargers are on a two-game winning streak, improving to 8-6 overall, and they can clinch a playoff berth with a win. Nick Foles will get the start for the Colts as they turn to their third different starter this season.
Kickoff is set for 8:15 p.m. ET. Los Angeles is a 4-point favorite in the latest Chargers vs. Colts odds from Caesars Sportsbook. The over/under for total points is set at 45, down 5.5 points from the opening line. Before locking in any Colts vs. Chargers picks, be sure to check out the NFL predictions and betting advice from SportsLine’s advanced computer model.
The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 16 of the 2022 NFL season on an incredible 157-113 run on top-rated NFL picks that dates back to the 2017 season.
The model ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.
Now, the model has set its sights on Chargers vs. Colts and just locked in its picks and MNF predictions. You can head to SportsLine now to see the model’s picks. Here are several NFL odds and betting lines and trends for Colts vs. Chargers:
Los Angeles should greatly benefit from the struggles of Indianapolis on offense. The Colts have more turnovers (27) than any team in the league, and Indianapolis also has the most lost fumbles (13) in the NFL. Indianapolis ranks No. 31 in red zone efficiency, No. 27 in third down efficiency, and No. 24 in total offense, with the Colts averaging only 17.5 points per game. The Colts are also now missing star running back Jonathan Taylor (ankle) for the rest of the year.
The Colts are in the bottom third of the league in first downs, touchdown passes, rushing yards, and rushing touchdowns, with Los Angeles suddenly playing better football on defense. The Chargers are giving up 15.5 points per game in the last two weeks, yielding only 251.5 total yards per game and 4.8 yards per play in those two victories. Los Angeles has forced 18 turnovers, an above-average figure, and the Chargers are above-average in red zone efficiency allowed at 53.5%. See which side to back here.
Indianapolis can key on the pass against Los Angeles. The Chargers are No. 31 in the NFL in rushing yards and No. 31 in the NFL in yards per carry. That makes life easier for the Colts, and Los Angeles is also No. 26 in the league in red zone efficiency at 49.0%. The Colts are giving up only 4.1 yards per carry to opponents, a top-eight mark in the NFL, and Indianapolis already stout against the pass.
The Colts give up 6.0 net yards per attempt and 205.6 yards per game through the air, and Indianapolis is in the top 12 of the NFL in total defense. The Colts are in the top five of the league in yards allowed per drive (27.5), and Indianapolis is in the top quartile of the league in third down efficiency allowed at 36.8%. With a tackling machine in Zaire Franklin in the middle of the defense, the Colts can be confident in at least slowing the Chargers. See which side to back here.
SportsLine’s model is leaning Over on the total, projecting 47 combined points. The model also says one side of the spread hits more than 50% of the time. You can only see the model’s MNF picks at SportsLine.
So who wins Chargers vs. Colts? And which side of the spread hits more than 50% of the time? Visit SportsLine now to see which side of the Chargers vs. Colts spread you need to jump on Monday, all from the model that has crushed its NFL picks, and find out.
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