USC vs. Stanford odds, prediction, line: 2022 Week 2 college football picks from model on 48-37 run – CBS Sports

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Pac-12 foes square off when the No. 10 USC Trojans (1-0) travel to play the Stanford Cardinal (1-0) on Saturday evening. This will be the first conference road test for Lincoln Riley’s squad. In 2021, the Cardinal defeated the Trojans 42-28. USC leads the all-time series 64-34-3.
Kickoff is set for 7:30 p.m. ET at Stanford Stadium. Caesars Sportsbook lists the Trojans as 9.5-point favorites in the latest USC vs. Stanford odds. The over/under for total points is set at 65. Before making any Stanford vs. USC picks, be sure to check out the college football predictions and betting advice from SportsLine’s proven model.
The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,500 for $100 players on its top-rated college football picks against the spread. It enters Week 2 of the 2022 college football season on a 48-37 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.
Now, the model has set its sights on USC vs. Stanford and just revealed its picks and predictions. You can visit SportsLine now to see the model’s picks. Now, here are several college football odds and trends for Stanford vs. USC:
High-impact transfers such as quarterback Caleb Williams are giving this USC program a boost in Year 1 under Lincoln Riley. Junior receiver Jordan Addison is another one of the big names who joined this team. Addison has elite agility and great speed with sure hands. The Maryland native can stop on a dime and has an exceptional change of direction. Addison secured the 2021 Biletnikoff Award in Pittsburgh after putting up 100 catches for 1,593 yards and 17 touchdowns.
Addison quickly made an impact in his first game action for the Trojans. Last week, he reeled in five passes for 54 yards and two scores. Sophomore receiver Mario Williams is another deep threat for this group. Williams can blow by defenders and consistently stretch the field. In 2021 as an Oklahoma Sooner, he snagged 35 passes for 380 yards and four touchdowns. 
Last season the Cardinal struggled to get the ground game going. They finished the campaign ranked last in the Pac-12 in rushing yards per game (87.3). Stanford is looking to change that and it got off to a solid start in the opener. It rushed for 159 yards and were headlined by junior running back E.J. Smith, the son of legendary NFL running back Emmitt Smith. Smith led the squad with 11 carries for 118 yards and two scores.
Senior receiver Michael Wilson made a serious impact on this offense against Colgate. Wilson was able to consistently break the top off the defense for deep shots down the field. The California native snagged five passes for 82 yards and two touchdowns. He also averaged 16.4 yards per reception. 
SportsLine’s model is leaning Over on the total, projecting the teams to combine for 69 points. The model also says one side of the spread hits in well over 70% of simulations. You can only get the model’s USC vs. Stanford pick at SportsLine
So who wins USC vs. Stanford? And which side of the spread hits in well over 70% of simulations? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has crushed its college football picks, and find out.  
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